Statistical Methods in Genetic Epidemiology
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Book Overview This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on d...
This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.
Book Details Format: Hardcover | Pages: 435 | Language: English | Publisher: OXFORD UNIV PR | ISBN: 019515939X
FormatHardcover
Pages435
LanguageEnglish
ISBN019515939X
EAN9780195159394
PublisherOXFORD UNIV PR
Publication Date1970-01-01
Edition1
AccessoriesNo Accessory
ConditionNew
Product TypeHARD COVER BOOKS
Weight1.76 Pounds
Length9.4 Inches
Width6.46 Inches
Height1.03 Inches
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