A Mathematical Modeling Approach to Infectious Diseases
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Book Overview The intent of this book is to provide a methodology for the analysis of infectious diseases by computer-based mathematical models. The ap...
The intent of this book is to provide a methodology for the analysis of infectious diseases by computer-based mathematical models. The approach is based on ordinary differential equations (ODEs) that provide time variation of the model dependent variables and partial differential equations (PDEs) that provide time and spatial (spatiotemporal) variations of the model dependent variables.
The starting point is a basic ODE SIR (Susceptible Infected Recovered) model that defines the S, I, R populations as a function of time. The ODE SIR model is then exended to PDEs that demonstrate the spatiotemporal evolution of the S, I, R populations. A unique feature of the PDE model is the use of cross diffusion between populations, a nonlinear effect that is readily accommodated numerically. A second feature is the use of radial coordinates to represent the geographical distribution of the model populations.
The numerical methods for the computer implementation of ODE/PDE models for infectious diseases are illustrated with documented R routines for particular applications, including models for malaria and the Zika virus. The R routines are available from a download so that the reader can reproduce the reported solutions, then extend the applications through computer experimentation, including the addition of postulated effects and associated equations, and the implementation of alternative models of interest.
The ODE/PDE methodology is open ended and facilitates the development of computer-based models which hopefully can elucidate the causes/conditions of infectious disease evolution and suggest methods of control.
Book Details Format: Hardcover | Pages: 447 | Language: English | Publisher: WORLD SCIENTIFIC PUB CO INC | ISBN: 981323878X
FormatHardcover
Pages447
LanguageEnglish
ISBN981323878X
EAN9789813238787
PublisherWORLD SCIENTIFIC PUB CO INC
Publication Date1970-01-01
Edition1
AccessoriesNo Accessory
ConditionNew
Product TypeHARD COVER BOOKS
Weight1.72 Pounds
Length9.0 Inches
Width6.0 Inches
Height1.0 Inches
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