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Brain Defenders: Harness the Power of Your Immune Cells to Protect Your Brain for Life

by David, M. D. Perlmutter

The immune system and brain health

Regular price $27.20 USD
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Awards & Recognition

  • Bestseller

    Instant New York Times bestseller

  • Author recognition

    #1 New York Times bestselling author

    The description identifies David Perlmutter as a #1 New York Times bestselling author.

AlbakiReads Editorial

The immune system and brain health

Neurologist David Perlmutter centers the book on microglia, immune cells in the brain, and their relationship to inflammation, metabolism, and neurological health. The chapters connect this biological framework to conditions including Alzheimer’s, Parkinson’s, depression, and long COVID, then discuss lifestyle factors and possible interventions such as sleep, fasting, oxygen therapy, metformin, and lion’s mane mushroom. Health recommendations and scientific claims here are presented as the book’s subject matter, not independently verified guidance.

Good fit for readers who enjoy

  • Adults interested in the relationship between immune function, metabolism, and brain health.
  • Readers seeking a popular-health overview of inflammation and conditions such as dementia, Parkinson’s, depression, or long COVID.
  • Those interested in the book’s discussion of lifestyle factors and therapeutic interventions related to cognitive health.

Themes

Microglia and brain immunityInflammation and neurological conditionsMetabolic health and cognitionLifestyle factors and brain resilience

Based on publisher information and book metadata.

Book overview

INSTANT NEW YORK TIMES BESTSELLER

From #1 New York Times bestselling author Dr. David Perlmutter comes a groundbreaking guide to the brain's immune cells--essential to preventing disease and sustaining peak cognitive function and mental health


We've been fighting the wrong enemy. For decades, medicine has pointed its weapons at symptoms like memory loss, tremors, headaches, and lethargy, while ignoring the root causes of diseases like Alzheimer's, Parkinson's, and major depression. In Brain Defenders, neurologist Dr. David Perlmutter flips the script, exposing the real culprits: malfunctioning microglia, tiny immune cells that, when metabolically hijacked, go rogue and attack the very neurons they're meant to protect.
With clarity and urgency, Dr. Perlmutter explains how a silent battle rages in the brain. Microglia can become either warriors of protection or agents of destruction--and the outcome depends largely on how we live. In Brain Defenders, you will:
  • Learn the science of immunometabolism and the relationship between energy and your cells
  • Understand the overlooked role of inflammation in everything from dementia to long COVID--and why the immune system may be the brain's greatest threat and hope
  • Discover how your lifestyle affects the fate of your microglia and, in turn, your cognitive future
  • Uncover the surprising link between metabolic health and brain resilience, and how tools like fasting, sleep, and even oxygen therapy can restore damaged neural networks
  • Explore therapeutic interventions--from metformin to lion's mane mushroom--that support healing and slow neural decline
Neurodegeneration, cognitive impairment, and mood disorders are not inevitable, but often the result of chronic, controllable inflammation. Drawing on the latest peer-reviewed science and grounded in decades of neurological care, Dr. Perlmutter delivers a powerful message: the future of your brain health is in your hands.
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