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The Book of Man: The Human Genome Project and the Quest to Discover Our Genetic Heritage

by Walter Bodmer

A late-1990s guide to the genome project and its human stakes

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Paperback New English

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AlbakiReads Editorial

A late-1990s guide to the genome project and its human stakes

Framed around the Human Genome Project, this book connects the reading of DNA with larger questions about inheritance, disease, human evolution, and individual difference. It places the project in a longer scientific history reaching back to Mendel’s work on heredity, while also addressing applied areas such as forensic science and genetic engineering. The discussion extends beyond laboratory discovery to the ethical and public consequences of expanding genetic knowledge. Written at a moment when the project was still underway, it presents genetic literacy as necessary for weighing the promises and dilemmas attached to decoding the human genome.

Good fit for readers who enjoy

  • Readers seeking an accessible historical introduction to the Human Genome Project
  • Those interested in genetics, heredity, and human evolution
  • Readers exploring ethical questions around genetic engineering and forensic DNA

Themes

Human Genome ProjectGenetic inheritanceDNA and diseaseForensic scienceEthics of genetic engineering

Based on publisher information and book metadata.

Book overview

James Watson, a discoverer of the structure of DNA, described it as "the most golden of molecules," the true chemical for life. Indeed, it is the essential component from which our genes are made. In it is encoded the genetic language that controls our destinies. Astonishingly powerful, just six millionths of a gram of DNA carries as much information as ten volumes of the Oxford English Dictionary.
The "Book of Man," is the term used by Walter Bodmer and Robin McKie for the DNA that is the instruction set according to which all humans are made. At conception, a single cell--the fertilized egg--is produced, and it is this one cell that has the potential to form a new and unique individual under the guidance of the DNA within its nucleus. The human body is made up of a hundred million million cells of many different sorts, and all contain the inherited information that comes from that first, single cell created at fertilization. Bodmer and McKie assert that when we learn how to read DNA's pages and chapters we will obtain the information relevant to the understanding of most diseases, individual differences in behavior, and a new awareness of our own history and evolution. The Book of Man explores how genetic information is now being read and interpreted by focusing on biology's most ambitious undertaking to date--the Human Genome Project, an attempt to uncover all the 100,000 genes that control our development and detail the DNA alphabet of each. The authors go on to wrestle with the moral and ethical issues of modern genetics, making a case for a rational appraisal of genetic engineering and for the public to become sufficiently "DNA literate" in order to appreciate the crucial role it plays in our lives.
From Gregor Mendel's discovery of the laws of inheritance to the high-tech, crime-stopping power of forensics science and the fascinating but sometimes troublesome implications of the latest science of genetic engineering, The Book of Man brilliantly explores and explains the quest that is changing our understanding of what it means to be a human being.
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